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The Carlat Psychiatry Podcast

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The Carlat Psychiatry Podcast

The Carlat Psychiatry Podcast

14 Reasons Why Psychopharmacology Differs in Women, Part 3

July 06, 2026 1:00am 18 min

Estrogen shapes nearly every neurotransmitter system in the brain, and when it starts to fall, psychiatric disorders often follow. This episode walks through what psychiatrists need to know about the perimenopause: which...

14 Reasons Why Psychopharmacology Differs in Women, Part 2

June 29, 2026 1:00am 23 min

Premenstrual hormones can destabilize mood, worsen ADHD, trigger psychosis, and drive binge eating. This episode walks through the tools to manage hormonal fluctuations in female patients, from SSRIs to overlooked supple...

14 Reasons Why Psychopharmacology Differs in Women, Part 1

June 22, 2026 1:00am 17 min

Women and men respond to psychiatric medications differently. In this first of a four-part series, Chris Aiken and Kellie Newsome walk through why valproate is risky for women, and when it’s worth using; why the FDA cut ...

Psilocybin: What You Need to Know

June 15, 2026 1:00am 18 min

Psilocybin is going mainstream: Trump has signed an executive order opening psychedelics to patients with severe mental illness, and one in eight American adults has already tried it. But as we dig into the research, a m...

EMDR in Practice: A Clinician's Guide to Trauma Reprocessing with Roger Solomon, PhD

June 08, 2026 1:00am 30 min

Dr. Roger Solomon provides a comprehensive introduction to Eye Movement Desensitization and Reprocessing (EMDR), explaining the adaptive information processing model that underlies the treatment, walking through all eigh...

Why We Miss Suicide Risk in Autistic Youth

June 01, 2026 1:00am 18 min

What if the patients we assume are safest from suicide are actually the ones we miss? Today we're talking about suicide risk in autistic youth, why it's higher than many clinicians expect, how distress shows up different...

Gender Affirming Care in Exile: Origins

May 25, 2026 1:00am 11 min

It's 1979, and Johns Hopkins has just shut down the first gender surgery clinic in the US. But investigations into the biological roots of gender identity are about to reopen those doors — and reshape how medicine thinks...

Gender Affirming Care: Fall of the House of Hopkins

May 18, 2026 1:00am 13 min

In 1966, Johns Hopkins opened the first gender surgery clinic in the US. Thirteen years later, a single study shut it down. We examine what the research said, what it didn't say, and how new standards of care emerged fro...

Gender Affirming Care in Exile: Targeting the Leader

May 11, 2026 1:00am 16 min

The president of the US branch of WPATH built one of the largest youth gender clinics in the country, then watched it close under political fire. Now she's facing a malpractice lawsuit from a former patient. We examine t...

Gender Affirming Care in Exile: The Trials

May 04, 2026 1:00am 13 min

Medical societies are reversing decades of support for gender-affirming care in youth — but is it the science driving the shift, or the politics? This episode walks through the evidence, from randomized trials to regret ...

Gender Affirming Care in Exile: The Lawsuits

April 27, 2026 1:00am 12 min

Two malpractice cases — one worth $2 million — are reshaping the standards of gender-affirming care. This episode traces what went wrong, what held up in court, and what every clinician needs to know when referring patie...

Lithium Goes Mainstream

April 20, 2026 1:00am 16 min

In the 1950s, a young Danish psychiatrist named Mogens Schou staked his career — and his family — on a mineral most of his colleagues dismissed as dangerous nonsense. This is the story of how lithium went from fringe cur...

Treating BPD Series Ep 2: Transference-Focused Psychotherapy—From Splitting to Coherence with Frank Yeomans, MD, PhD

April 16, 2026 1:00am 40 min

Dr. Frank Yeomans is an Adjunct Associate Clinical Professor of Psychiatry at Columbia University Vagelos College of Physicians and Surgeons. He is one of the developers of Transference-Focused Psychotherapy (TFP). In th...

Lithium: From 7UP to Table Salt

April 13, 2026 1:00am 12 min

Before lithium became a cornerstone of psychiatry, it was in soda, spa water, and salt shakers. Trace lithium’s journey from Victorian health fad to life-saving mood stabilizer, and discover why the uric acid theory that...

When Autism Meets the Legal System: A Clinician’s Guide

April 06, 2026 1:00am 19 min

Legal questions come up in clinical care of autistic children and adults more often than many of us expect. A parent asks for a custody letter; a school requests documentation for services; a patient asks about disabilit...

Jeffrey Epstein on the Couch: Part IV

March 30, 2026 1:00am 12 min

Narcissism, antisocial, pedophilia… A lot of psychiatric terms have been used to explain Jeffrey Epstein. We’ll look at what fits.CME: Take the CME Post-Test for this EpisodePublished On: 03/30/2026Duration: 12 minutes, ...

Jeffrey Epstein on the Couch: Part III

March 23, 2026 1:00am 23 min

Narcissism, antisocial, pedophilia… A lot of psychiatric terms have been used to explain Jeffrey Epstein. We’ll look at what fits.CME: Take the CME Post-Test for this EpisodePublished On: 03/23/2026Duration: 23 minutes, ...

Jeffery Epstein on the Couch: Part II

March 16, 2026 1:00am 16 min

Does money lead to happiness? What kind of stress causes depression? Why the FDA change their requirements for new drug approvals? And what happened between Jeffrey Epstein and Ghislaine Maxwell that launched an enterpri...

Jeffrey Epstein on the Couch: Part I

March 09, 2026 1:00am 15 min

Narcissism, antisocial, pedophilia… We examine the diagnoses people invoke to explain Jeffrey Epstein and determine if any fit. CME: Take the CME Post-Test for this EpisodePublished On: 03/09/2026Duration: 15 minutes, 29...

Hidden Gems: Pramipexole Part II

March 02, 2026 1:00am 19 min

Pramipexole has moved up the in our algorithm for treatment resistant depression. Today, learn how to use this dopamine agonist.CME: Take the CME Post-Test for this EpisodePublished On: 03/02/2026Duration: 19 minutes, 24...

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